On-chip microtubule gliding assay for parallel measurement of tau protein species-Reference-Cited by-同舟云学术

On-chip microtubule gliding assay for parallel measurement of tau protein species

Published:2016 Issue:9 Volume:16 Page:1691-1697
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Subramaniyan Parimalam Subhathirai¹²³⁴,Tarhan Mehmet C.⁵⁶⁷⁴⁸,Karsten Stanislav L.⁸⁶⁷⁴⁹,Fujita Hiroyuki⁸⁶⁷⁴,Shintaku Hirofumi¹²³⁴,Kotera Hidetoshi¹²³⁴,Yokokawa Ryuji¹²³⁴

Affiliation:

1. Department of Micro Engineering

2. Kyoto University

3. Kyoto

4. Japan

5. Laboratory for Integrated Micro Mechatronic Systems (LIMMS)

6. Institute of Industrial Science (IIS)

7. The University of Tokyo

8. Center for International Research on Micronano Mechatronics (CIRMM)

9. NeuroInDx Inc.

Abstract

Rapid on-chip detection of tau isoforms, their ratios and mutants by measuring the fluorescent intensity of microtubules in a kinesin-coated microfluidic device.

Funder

Japan Society for the Promotion of Science

National Institute of Mental Health

Ministry of Education, Culture, Sports, Science, and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/LC/C5LC01486G

Reference41 articles.

1. Emerging Concepts in Alzheimer's Disease