PIDA-mediated N–N bond formation to access pyrazolidine-3,5-diones: a novel process for uricosuric agents G-25671 and sulfinpyrazone-Reference-Cited by-同舟云学术

PIDA-mediated N–N bond formation to access pyrazolidine-3,5-diones: a novel process for uricosuric agents G-25671 and sulfinpyrazone

Published:2023 Issue:53 Volume:59 Page:8242-8245
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Halder Priyanka¹²,Mhaske Santosh B.¹²^ORCID

Affiliation:

1. Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune – 411008, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad – 201002, India

Abstract

An efficient PIDA-mediated intramolecular dehydrogenative N–N bond formation protocol has been established to access the pyrazolidine-3,5-dione core of sulfinpyrazone class of drugs by avoiding carcinogenic and expensive diphenylhydrazines.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC02078A

Reference48 articles.

1. Synthesis and Characterization of Novel and Promising 1,2,4,4‐Tetranitropyrazolidine‐3,5‐dione for High Energy Materials Application †

2. Antimicrobial activity of newly Synthesized Pyrazolidine-3, 5-dione Substituted Thiochromene Derivatives

3. Pyrazolidine-3,5-diones and 5-Hydroxy-1H-pyrazol-3(2H)-ones, Inhibitors of UDP-N-acetylenolpyruvyl Glucosamine Reductase

4. Synthesis of 4-alkyl-1,2-diphenyl-3,5-dioxopyrazolidines possessing aryl methylsulfonyl and sulfonamide pharmacophores for evaluation as selective cyclooxygenase-2 (COX-2) inhibitors

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