Effective asymmetric vinylogous Mannich reaction of isatin imines with α,α-dicyanoolefins in the presence of a simple chiral amide phosphonium bifunctional phase transfer catalyst-Reference-Cited by-同舟云学术

Effective asymmetric vinylogous Mannich reaction of isatin imines with α,α-dicyanoolefins in the presence of a simple chiral amide phosphonium bifunctional phase transfer catalyst

Published:2017 Issue:1 Volume:4 Page:101-114
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Cheng Cang¹²³⁴,Lu Xuehe¹²³⁴,Ge Luo¹²³⁴,Chen Jie¹²³⁴,Cao Weiguo¹²³⁴,Wu Xiaoyu¹²³⁴⁵,Zhao Gang⁵⁶⁷⁸⁴

Affiliation:

1. Department of Chemistry

2. Shanghai University

3. Shanghai 200444

4. China

5. Key Laboratory of Synthetic Chemistry of Natural Substances

6. Shanghai Institute of Organic Chemistry

7. Chinese Academy of Sciences

8. Shanghai 200032

Abstract

A Mannich reaction between N-Boc isatin imine and α,α-dicyanoolefin as well as subsequent oxidative cleavage of the malonic nitrile moiety were described.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/QO/C6QO00546B

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