Efficient regioselective enzymatic acylation of troxerutin: difference characterization of in vitro cellular uptake and cytotoxicity

Author:

Hao Li-sha1,Zhang Meng-meng2ORCID,Li Xiao-Feng1ORCID,Xin Xuan3,Zhao Guang-lei4ORCID

Affiliation:

1. School of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, South China University of Technology, Wushan Road 381, Guangzhou 510640, China

2. College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Dongsha Street 24, Guangzhou, Guangdong, 510225, China

3. College of Light Industry and Food Technology, Zhongkai University of Agriculture and Engineering, Dongsha Street 24, Guangzhou, Guangdong, 510225, China

4. State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Wushan Road 381, Guangzhou, Guangdong, 510640, China

Abstract

Multi-site acylation of troxerutin can solve the problems of cytotoxicity and rapid hydrolysis of ester bonds caused by mono-acylation and increase cellular uptake.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3