Thermodynamic epimeric equilibration and crystallisation-induced dynamic resolution of lobelanine, norlobelanine and related analogues-Reference-Cited by-同舟云学术

Thermodynamic epimeric equilibration and crystallisation-induced dynamic resolution of lobelanine, norlobelanine and related analogues

Published:2014 Issue:48 Volume:12 Page:9797-9810
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Amara Z.¹²³⁴⁵,Bernadat G.¹²³⁶⁵,Venot P.-E.¹²³⁴⁵,Retailleau P.⁷⁸⁹,Troufflard C.¹²¹⁰⁵,Drège E.¹²³⁴⁵,Le Bideau F.¹²³⁴⁵,Joseph D.¹²³⁴⁵

Affiliation:

1. Université Paris-Sud

2. UMR CNRS 8076 BioCIS

3. LabEx Lermit

4. Equipe de Chimie des Substances Naturelles

5. F-92296 Châtenay-Malabry, France

6. Molécules Fluorées et Chimie Médicinale

7. Institut de Chimie des Substances Naturelles

8. UPR CNRS 2301

9. F-91198 Gif-sur-Yvette, France

10. Service commun d'analyses

Abstract

The step-economical synthesis of lobelanine involving a ring closing double aza-Michael (RCDAM) reaction is revisited and successfully extended to the synthesis of various configurationally more stable analogues.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB01787K

Reference55 articles.

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