Towards more accurate solubility measurements with real time monitoring: a carvedilol case study-Reference-Cited by-同舟云学术

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Towards more accurate solubility measurements with real time monitoring: a carvedilol case study

Published:2021 Issue:26 Volume:45 Page:11618-11625
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Csicsák Dóra¹²³⁴,Borbás Enikő⁵⁶⁷⁴^ORCID,Kádár Szabina⁵⁶⁷⁴,Tőzsér Petra⁵⁶⁷⁴,Bagi Péter⁵⁶⁷⁴^ORCID,Pataki Hajnalka⁵⁶⁷⁴,Sinkó Bálint⁸⁹¹⁰,Takács-Novák Krisztina¹²³⁴,Völgyi Gergely¹²³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry

2. Semmelweis University

3. H-1092 Budapest

4. Hungary

5. Department of Organic Chemistry and Technology

6. Budapest University of Technology and Economics

7. Budapest

8. Pion Inc. Billerica

9. Massachusetts 01821

10. USA

Abstract

Study of factors like type of polymorphs, pH and buffer composition influencing the equilibrium time of carvedilol using in situ UV-probes.

Funder

Magyar Tudományos Akadémia

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D1NJ01349A

Reference33 articles.

1. A. Avdeef , Absorption and Drug Development: Solubility, Permeability, and Charge State , 2012

2. Analysis of organic polymorphs. A review

3. H. G. Brittain , Polymorphism in Pharmaceutical Solids , 2nd edn, 2016

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1. Bioequivalence prediction with small-scale biphasic dissolution and simultaneous dissolution-permeation apparatus—An aripiprazole case study;European Journal of Pharmaceutical Sciences;2024-07

2. Thermodynamic consideration of dissolution and distribution behavior of carvedilol in pharmaceutical significant media;The Journal of Chemical Thermodynamics;2024-03

3. Ultrasound-assisted continuous crystallization of metastable polymorphic pharmaceutical in a slug-flow tubular crystallizer;Ultrasonics Sonochemistry;2023-11

4. Preparation and Characterization of Carvedilol Solid Dispersion by Kneading Method;Al Mustansiriyah Journal of Pharmaceutical Sciences;2023-10-09

5. The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character;Pharmaceutics;2023-01-13

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