2D green SPPS: green solvents for on-resin removal of acid sensitive protecting groups and lactamization-Reference-Cited by-同舟云学术

2D green SPPS: green solvents for on-resin removal of acid sensitive protecting groups and lactamization

Published:2019 Issue:10 Volume:21 Page:2594-2600
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Pawlas Jan¹²³^ORCID,Antonic Biljana¹²³,Lundqvist Marika¹²³,Svensson Thomas¹²³,Finnman Jens¹²³,Rasmussen Jon H.¹²³

Affiliation:

1. PolyPeptide Group

2. 20061 Limhamn

3. Sweden

Abstract

An SPPS method for the on-resin removal of acid labile protecting groups using TFA/TIS in EtOAc/MeCN and lactamization with PyBOP/DIEA in NBP/EtOAc is reported.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/GC/C9GC00898E

Reference84 articles.

1. The Green ChemisTREE: 20 years after taking root with the 12 principles

2. The E factor 25 years on: the rise of green chemistry and sustainability

3. Inspiring process innovation via an improved green manufacturing metric: iGAL

4. Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited

5. Therapeutic peptides: Historical perspectives, current development trends, and future directions

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