A facile, practical and metal-free microwave-assisted protocol for mono- and bis-[1,2,4]triazolo[1,5-a]pyridines synthesis utilizing 1-amino-2-imino-pyridine derivatives as versatile precursors
Author:
Affiliation:
1. Chemistry Department
2. Faculty of Science
3. Fayoum University
4. Fayoum
5. Egypt
6. Kuwait University
7. Safat 13060
8. Kuwait
Abstract
A novel and highly efficient, protocol for synthesizing mono- and bis-[1,2,4]triazolo[1,5-a]pyridines has been established utilizing the readily attainable 1-amino-2-imino-pyridines and microwave irradiation as green energy source.
Funder
Kuwait University
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA02256J
Reference33 articles.
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2. The Diverse supramolecular synthons formed by 2-subsituted 5-morpholinomethylphenyl Triazolo[1,5-a]pyridines in solid state
3. Cyclization of Methyl-Coumalate-Derived Methyl 1-Benzamido-6-oxo-1,6-dihydropyridine-3-carboxylates: Assembly of the [1,2,4]Triazolo[1,5-a]pyridine Ring System
4. Discovery of 3-Cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-a]pyridine (JNJ-42153605): A Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor
5. 1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction
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