Alteration of epigenetic program to recover memory and alleviate neurodegeneration: prospects of multi-target molecules
Author:
Affiliation:
1. Institute for Integrated Cell-Material Sciences (iCeMS)
2. Kyoto University
3. Kyoto 606-8502, Japan
4. Department of Chemistry
5. Graduate School of Science
6. Kyoto 606-8501, Japan
Abstract
Next-generation sequence-specific small molecules modulating the epigenetic enzymes (DNMT/HDAC) and signalling factors can precisely turn ‘ON’ the multi-gene network in a neural cell.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2014/BM/C4BM00068D
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