Synthesis of iminosugar derivatives presenting naphthyl and alkyl amine interacting groups and binding to somatostatin receptors-Reference-Cited by-同舟云学术

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Synthesis of iminosugar derivatives presenting naphthyl and alkyl amine interacting groups and binding to somatostatin receptors

Published:2014 Issue:8 Volume:5 Page:1150-1158
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Barron Stephen¹²³⁴,Murphy Paul V.⁵⁶⁷⁴

Affiliation:

1. School of Chemistry and Chemical Biology

2. University College Dublin

3. Dublin 4

4. Ireland

5. School of Chemistry

6. National University of Ireland Galway

7. Galway

Abstract

The synthesis of 1-deoxynojirimycin (DNJ) derivatives, presenting a 2-naphthylmethyl and an alkyl amino side chain, from l-sorbose is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MD/C4MD00074A

Reference37 articles.

1. Carbohydrate‐Based Molecular Scaffolding

2. Carbohydrates as Scaffolds in Drug Discovery

3. Syntheses of Peptidomimetics Based on Pyranose and Polyhydroxylated Piperidine Scaffolds

4. Synthesis and Conformational Analysis of Linear and Cyclic Peptides Containing Sugar Amino Acids

5. Sugar amino acids at the anomeric position of carbohydrates: synthesis of spirocyclic amino acids of 6-deoxy-l-lyxofuranose

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cyclisations and Strategies for Stereoselective Synthesis of Piperidine Iminosugars;The Chemical Record;2021-10-28

2. Multicomponent Approach to Homo- and Hetero-Multivalent Glycomimetics Bearing Rare Monosaccharides;The Journal of Organic Chemistry;2020-01-31

3. Ligand design for somatostatin receptor isoforms 4 and 5;European Journal of Medicinal Chemistry;2019-02

4. Synthesis of 1-Deoxynojirimycin: Exploration of Optimised Conditions for Reductive Amidation and Separation of Epimers;Journal of Chemical Research;2017-08

5. Allylic Azide Rearrangement in Tandem with Intramolecular Huisgen Cycloaddition for Iminosugar and Glycomimetic Synthesis: Functionalized Piperidine, Pyrrolidine, and Pyrrolotriazoles from d-Mannose;Synthesis;2017-04-20

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