Biocompatible poly(N-(ω-acryloyloxy-n-alkyl)-2-pyrrolidone)s with widely-tunable lower critical solution temperatures (LCSTs): a promising alternative to poly(N-isopropylacrylamide)

Author:

Nishimura Shin-nosuke1ORCID,Nishida Kei1ORCID,Ueda Tomoya2,Shiomoto Shohei1ORCID,Tanaka Masaru12ORCID

Affiliation:

1. Institute for Materials Chemistry and Engineering, Kyushu University, 744, Moto-oka, Nishi-ku, Fukuoka, 819-0395, Japan

2. Gladuate School of Engineering, Kyushu University, 744, Moto-oka, Nishi-ku, Fukuoka, 819-0395, Japan

Abstract

The biocompatible (co)polymers undergoes a thermal stimulus-driven liquid–liquid phase separation and form coacervates above the lower critical solution temperature (LCST). The LCSTs are able to be precisely controlled between 0 °C and 100 °C.

Funder

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

Nakayama Foundation for Human Science

Japan Prize Foundation

AGC

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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