Revealing light-induced structural shifts in G-quadruplex-porphyrin complexes: a pulsed dipolar EPR study-Reference-Cited by-同舟云学术

Revealing light-induced structural shifts in G-quadruplex-porphyrin complexes: a pulsed dipolar EPR study

Published:2023 Issue:33 Volume:25 Page:22455-22466
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Sannikova Natalya E.¹²^ORCID,Kolokolov Mikhail I.¹²^ORCID,Khlynova Tamara A.¹²^ORCID,Chubarov Alexey S.³²^ORCID,Polienko Yuliya F.⁴^ORCID,Fedin Matvey V.¹²^ORCID,Krumkacheva Olesya A.¹²^ORCID

Affiliation:

1. International Tomography Center SB RAS, 630090 Novosibirsk, Russia

2. Novosibirsk State University, Pirogova Str. 2, Novosibirsk 630090, Russia

3. Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk 630090, Russia

4. N.N. Vorozhtsov Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia

Abstract

Pulsed EPR spectroscopy effectively monitors light-induced structural alterations in complexes of G-quadruplexes with photosensitizers, revealing G-quadruplex unfolding and the formation of dimeric structures.

Funder

Russian Science Foundation

Ministry of Science and Higher Education of the Russian Federation

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CP/D3CP01775C

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5. Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

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