Human-origin Lactobacillus salivarius AR809 protects against immunosuppression in S. aureus-induced pharyngitis via Akt-mediated NF-κB and autophagy signaling pathways

Author:

Jia Guochao12345,Liu Xiaofeng12345,Che Na67895,Xia Yongjun12345,Wang Guangqiang12345,Xiong Zhiqiang12345,Zhang Hui12345,Ai Lianzhong12345ORCID

Affiliation:

1. Shanghai Engineering Research Center of Food Microbiology

2. School of Medical Instrument and Food Engineering

3. University of Shanghai for Science and Technology

4. Shanghai 200093

5. China

6. Department of Otolaryngology

7. Tongji Hospital

8. Tongji University

9. Shanghai 200065

Abstract

Lactobacillus salivarius AR809 is a newly discovered probiotic strain from a healthy human pharynx and has potential ability to adhere to the pharyngeal epithelium and inhibit Staphylococcus aureus (S. aureus)-induced inflammatory response.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Tongji University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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