Methylated derivatives of myricetin enhance life span in Caenorhabditis elegans dependent on the transcription factor DAF-16

Author:

Büchter C.12345,Ackermann D.5674,Honnen S.5674,Arnold N.8934,Havermann S.12345,Koch K.1234,Wätjen W.12345

Affiliation:

1. Martin-Luther-Universität Halle-Wittenberg

2. Institute of Agricultural and Nutritional Sciences

3. D-06120 Halle/Saale

4. Germany

5. Institute of Toxicology

6. Heinrich Heine University Düsseldorf

7. D-40225 Düsseldorf

8. Department of Bioorganic Chemistry

9. Leibniz Institute of Plant Biochemistry

Abstract

Methylated derivatives of myricetin enhance the life span of the nematodeCaenorhabditis eleganscomparable to the non-methylated flavonoid myricetin. The life-prolonging effects are dependent on the transcription factor DAF-16.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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