Modulation of inflammation by anti-TNF α mAb-dendrimer nanoparticles loaded in tyramine-modified gellan gum hydrogels in a cartilage-on-a-chip model-Reference-Cited by-同舟云学术

Modulation of inflammation by anti-TNF α mAb-dendrimer nanoparticles loaded in tyramine-modified gellan gum hydrogels in a cartilage-on-a-chip model

Published:2021 Issue:20 Volume:9 Page:4211-4218
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Oliveira I. M.¹²³⁴⁵,Carvalho M. R.¹²³⁴⁵,Fernandes D. C.¹²³⁴⁵,Abreu C. M.¹²³⁴⁵^ORCID,Maia F. R.¹²³⁴⁵^ORCID,Pereira H.¹²³⁴⁵,Caballero D.¹²³⁴⁵^ORCID,Kundu S. C.¹²³⁴⁵,Reis R. L.¹²³⁴⁵,Oliveira J. M.¹²³⁴⁵^ORCID

Affiliation:

1. 3B's Research Group

2. I3Bs - Research Institute on Biomaterials

3. Biodegradables and Biomimetics of University of Minho

4. Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine

5. Avepark, Parque de Ciência e Tecnologia

Abstract

A human 3D inflammatory cartilage-on-a chip model was develop as a drug screening platform to evaluate the therapeutic efficacy of anti-TNFα mAb-CS/PAMAM dendrimer NPs loaded-Tyramine-Gellan Gum Hydrogel.

Funder

Fundação para a Ciência e a Tecnologia

Horizon 2020

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB00802A

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