Novel fluorescent lapachone-based BODIPY: synthesis, computational and electrochemical aspects, and subcellular localisation of a potent antitumour hybrid quinone-Reference-Cited by-同舟云学术

Novel fluorescent lapachone-based BODIPY: synthesis, computational and electrochemical aspects, and subcellular localisation of a potent antitumour hybrid quinone

Published:2016 Issue:90 Volume:52 Page:13281-13284
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Gontijo Talita B.¹²³⁴⁵,de Freitas Rossimiriam P.¹²³⁴⁵,de Lima Guilherme F.¹²³⁴⁵^ORCID,de Rezende Lucas C. D.⁶⁷⁸⁵,Pedrosa Leandro F.¹²⁹¹⁰⁵,Silva Thaissa L.¹¹¹²¹³⁵,F. Goulart Marilia O.¹¹¹²¹³⁵,Cavalcanti Bruno C.¹⁴¹⁵¹⁶⁵,Pessoa Claudia¹⁴¹⁵¹⁶⁵¹⁷,Bruno Marina P.¹⁸¹⁹²⁰⁵,Corrêa José R.¹⁸¹⁹²⁰⁵,Emery Flavio S.⁶⁷⁸⁵,da Silva Júnior Eufrânio N.¹²³⁴⁵

Affiliation:

1. Institute of Exact Sciences

2. Department of Chemistry

3. Federal University of Minas Gerais

4. Belo Horizonte

5. Brazil

6. Faculty of Pharmaceutical Sciences at Ribeirao Preto

7. University of São Paulo

8. Ribeirão Preto

9. Fluminense Federal University

10. Volta Redonda

11. Institute of Chemistry and Biotechnology

12. Federal University of Alagoas

13. Maceió

14. Department of Physiology and Pharmacology

15. Federal University of Ceará

16. Fortaleza

17. Fiocruz-Ceará

18. Institute of Chemistry

19. University of Brasília

20. Brasília

Abstract

A fully characterized fluorescent lapachone-based BODIPY, a specific mitochondrial-staining agent, is reported.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de Minas Gerais

Fundação de Amparo à Pesquisa do Estado de Alagoas

São Paulo Research Foundation

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC07054J

Reference27 articles.

1. Lapachol and its congeners as anticancer agents: a review

2. A novel triazolic naphthofuranquinone induces autophagy in reservosomes and impairment of mitosis in Trypanosoma cruzi

3. Novel naphthoquinone derivatives and evaluation of their trypanocidal and leishmanicidal activities

4. Synthetic 1,4-Pyran Naphthoquinones Are Potent Inhibitors of Dengue Virus Replication

5. Identification of β-Lapachone Analogs as Novel MALT1 Inhibitors To Treat an Aggressive Subtype of Diffuse Large B-Cell Lymphoma

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