Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts-Reference-Cited by-同舟云学术

Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts

Published:2023 Issue:11 Volume:11 Page:4022-4031
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Sommerfeld Sven D.¹^ORCID,Zhou Xianyu²³^ORCID,Mejías Joscelyn C.¹^ORCID,Oh Byoung Chol²,Maestas David R.¹⁴^ORCID,Furtmüller Georg J.²^ORCID,Laffont Philippe A.¹,Elisseeff Jennifer H.¹⁴^ORCID,Brandacher Gerald²

Affiliation:

1. Translational Tissue Engineering Center, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

2. Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA) Laboratory, Johns Hopkins School of Medicine, Baltimore, MD, USA

3. Department of Plastic and Reconstructive Surgery, the Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China

4. Department of Biomedical Engineering and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Abstract

ECM biomaterial implanted at the wound interface during a mouse hind limb allograft transplant improves allograft tolerance by working synergistically with costimulatory blockade (CTLA4-Ig) to modulate the local immune response.

Funder

Johns Hopkins Hospital

Office of Strategic Coordination

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D2BM01845D

Reference68 articles.

1. Current status of vascularized composite tissue allotransplantation