Naturally occurring FANCF–Hes1 complex inhibitors from Wrightia religiosa

Author:

Arai Midori A.1234,Uemura Kenji1234,Hamahiga Nozomi1234,Ishikawa Naoki1234,Koyano Takashi564,Kowithayakorn Thaworn78910,Kaddar Tagrid1112131415,Carreau Madeleine1112131415,Ishibashi Masami1234

Affiliation:

1. Graduate School of Pharmaceutical Sciences

2. Chiba University

3. Chuo-ku

4. Japan

5. Temko Corporation

6. Nakano

7. Faculty of Agriculture

8. Khon Kaen University

9. Khon Kaen 40002

10. Thailand

11. Department of Pediatrics Université Laval

12. Cité Universitaire, Québec, Canada, G1K 7P4

13. and the Centre de Recherche du CHU de Québec-CHUL

14. Québec

15. Canada G1V 4G2

Abstract

The first naturally occurring inhibitors of FANCF–Hes1 complex were isolated by a newly constructed protein-based high-throughput screening assay.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

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