Accelerated 13C detection by concentrating the NMR sample in a biphasic solvent system-Reference-Cited by-同舟云学术

Accelerated 13C detection by concentrating the NMR sample in a biphasic solvent system

Published:2021 Issue:21 Volume:146 Page:6582-6591
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Baishya Bikash¹^ORCID,Verma Ajay²,Parihar Rashmi¹³

Affiliation:

1. Centre of Biomedical Research (Formerly Centre of Biomedical Magnetic Resonance), SGPGIMS Campus, Raebareli Road, Lucknow, 226014, India

2. Govt. Degree College, Tyuni, 248199, Dehradun, Uttarakhand, India

3. Department of Bioinformatics, Dr A. P. J. Abdul Kalam Technical University, Lucknow-226021, U.P., India

Abstract

A biphasic solvent system of CDCl3 and H2O or D2O is used to concentrate solutes closer to the NMR coil. Up to 1.6–1.8 fold gain in the SNR is observed for 13C NMR and 1H–13C HSQC, reducing the experimental time by more than half.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AN/D1AN00470K

Reference13 articles.

1. NMR of natural products at the ‘nanomole-scale’

2. Could smaller really be better? Current and future trends in high-resolution microcoil NMR spectroscopy

3. Microcoil nuclear magnetic resonance spectroscopy

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5. Simple and Rapid (Extraction) Protocol for NMR Metabolomics—Direct Measurement of Hydrophilic and Hydrophobic Metabolites Using Slice Selection

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