Target specificity of mammalian DNA methylation and demethylation machinery
Author:
Affiliation:
1. Albert Einstein College of Medicine
2. 10461 Bronx
3. USA
4. BioMed X Innovation Center
5. Heidelberg D-69120
6. Germany
7. Universität Stuttgart
8. Abteilung Biochemie
9. Institute für Biochemie und Technische Biochemie
10. Stuttgart D-70569
Abstract
We review here the molecular mechanisms employed by DNMTs and TET enzymes that are responsible for shaping the DNA methylation pattern of a mammalian cell.
Funder
Deutsche Forschungsgemeinschaft
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB02574B
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