Fluorescence-based detection of single-nucleotide changes in RNA using graphene oxide and DNAzyme

Author:

Hong Chaesun1234,Kim Dong-Min1234,Baek Ahruem1234,Chung Hyewon5674,Jung Woong89104,Kim Dong-Eun1234

Affiliation:

1. Department of Bioscience and Biotechnology

2. Konkuk University

3. Seoul 143-701

4. Republic of Korea

5. Department of Ophthalmology

6. Konkuk University Medical Center

7. Seoul 134-729

8. Department of Emergency Medicine

9. Kyung Hee University Hospital at Gangdong

10. Seoul 134-727

Abstract

We report a simple fluorometric method for detection of single-nucleotide changes in RNA using graphene oxide (GO) and RNA-cleaving DNAzyme.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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