KOtBu-promoted synthesis of multi-substituted 4-aminopyrimidines from benzonitriles and aliphatic amides-Reference-Cited by-同舟云学术

KOtBu-promoted synthesis of multi-substituted 4-aminopyrimidines from benzonitriles and aliphatic amides

Published:2015 Issue:129 Volume:5 Page:106444-106447
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Feng Jian-Bo¹²³⁴⁵,Wu Xiao-Feng¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. Zhejiang Sci-Tech University

3. Hangzhou

4. People’s Republic of China

5. Leibniz-Institut für Katalyse e.V. an der Universität Rostock

Abstract

Multi-substituted 4-aminopyrimidines were prepared from commercially-available benzonitriles and aliphatic amides in transition-metal-free conditions. With KO^tBu as the only promoter, target pyrimidines were isolated in moderate to excellent yields.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA24292D

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