Stereoselective synthesis of macrocyclic peptides via a dual olefin metathesis and ethenolysis approach
Author:
Affiliation:
1. Arnold and Mabel Beckman Laboratories of Chemical Synthesis
2. Division of Chemistry and Chemical Engineering
3. California Institute of Technology
4. Pasadena
5. USA
Abstract
A metathesis strategy for controlling olefin geometry within macrocyclic peptides has been achieved using catalyst-directed RCM and ethenolysis.
Funder
NIH
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/SC/C5SC01507C
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