Pegylated metal-free and zinc(ii) phthalocyanines: synthesis, photophysicochemical properties and in vitro photodynamic activities against head, neck and colon cancer cell lines

Author:

Akkoç Berkay1ORCID,Samsunlu Taylan1ORCID,Işık Şeyma23,Özçeşmeci Mukaddes1ORCID,Atmaca Göknur Yaşa4,Erdoğmuş Ali4,Serhatlı Müge2,Hamuryudan Esin1ORCID

Affiliation:

1. Department of Chemistry, Istanbul Technical University, 34469, Maslak, Istanbul, Turkey

2. Genetic Engineering and Biotechnology Institute GEBI, TUBITAK Marmara Research Center MRC, 41470, Gebze, Kocaeli, Turkey

3. Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydınlar University, 34684, Atasehir, Istanbul, Turkey

4. Department of Chemistry, Yildiz Technical University, 34210, Esenler, Istanbul, Turkey

Abstract

PDT activities of water-soluble Pcs, which were synthesized and characterized in this study, were tested with in vitro studies on different cancer cell lines. According to the results, they are alternative structures in the PDT applications.

Funder

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

Istanbul Teknik Üniversitesi

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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