C(sp2)–H Trifluoromethylation of enamides using TMSCF3: access to trifluoromethylated isoindolinones, isoquinolinones, 2-pyridinones and other heterocycles-Reference-Cited by-同舟云学术

C(sp2)–H Trifluoromethylation of enamides using TMSCF3: access to trifluoromethylated isoindolinones, isoquinolinones, 2-pyridinones and other heterocycles

Published:2018 Issue:75 Volume:54 Page:10574-10577
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Krishnamurti Vinayak¹²³⁴,Munoz Socrates B.¹²³⁴^ORCID,Ispizua-Rodriguez Xanath¹²³⁴,Vickerman Jeffrey¹²³⁴,Mathew Thomas¹²³⁴^ORCID,Surya Prakash G. K.¹²³⁴^ORCID

Affiliation:

1. Loker Hydrocarbon Research Institute and Department of Chemistry

2. University of Southern California

3. Los Angeles

4. USA

Abstract

A method for the direct C(sp²)–H trifluoromethylation of enamides, including biologically relevant isoindolinones, isoquinolinones and 2-pyridinones using TMSCF₃ under oxidative conditions is presented.

Funder

Loker Hydrocarbon Research Institute, University of Southern California

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CC/C8CC04907F

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