Physiology, pathology and the biomolecular corona: the confounding factors in nanomedicine design-Reference-Cited by-同舟云学术

Physiology, pathology and the biomolecular corona: the confounding factors in nanomedicine design

Published:2022 Issue:6 Volume:14 Page:2136-2154
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Liu Kai¹^ORCID,Salvati Anna²^ORCID,Sabirsh Alan¹^ORCID

Affiliation:

1. Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg, Sweden

2. Department of Nanomedicine & Drug Targeting, Groningen Research Institute of Pharmacy, University of Groningen, Groningen 9713AV, The Netherlands

Abstract

Nanomedicines can acquire different biomolecular coronas from various biological contexts. This review offers a practical guide to tuning corona content to match physiological requirements as a necessary step for future nanomedicine success.

Funder

AstraZeneca

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D1NR08101B

Reference225 articles.

1. A Status Report on FDA Approval of Medical Devices Containing Nanostructured Materials

2. The COVID-19 vaccine development landscape

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4. The journey of a drug-carrier in the body: An anatomo-physiological perspective

5. Mechanism of hard-nanomaterial clearance by the liver

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