DNA radiosensitization by terpyridine-platinum: damage induced by 5 and 10 eV transient anions-Reference-Cited by-同舟云学术

DNA radiosensitization by terpyridine-platinum: damage induced by 5 and 10 eV transient anions

Published:2023 Issue:7 Volume:15 Page:3230-3242
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Ouyang Liangde¹,Lin Hong¹,Zhuang Puxiang¹,Shao Yu¹^ORCID,Khosravifarsani Meysam²,Guérin Brigitte²,Zheng Yi¹²^ORCID,Sanche Léon²^ORCID

Affiliation:

1. State Key Laboratory of Photocatalysis on Energy and Environment, Faculty of Chemistry, Fuzhou University, Fuzhou 350116, P.R. China

2. Department of Nuclear Medicine and Radiobiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada J1H 5N4

Abstract

The intercalation of the chemotherapeutic drug terpyridine-platinum within the G-quadruplex structure of DNA sensitizes cancer cells to the low energy electrons produced by ionizing radiation during radiotherapy.

Funder

Natural Sciences and Engineering Research Council of Canada

Canadian Institutes of Health Research

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D2NR05403E

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