Visible-light-mediated catalyst-free synthesis of trifluoromethyl(spiro)-epoxides bearing contiguous quaternary centers-Reference-Cited by-同舟云学术

Visible-light-mediated catalyst-free synthesis of trifluoromethyl(spiro)-epoxides bearing contiguous quaternary centers

Published:2024 Issue:11 Volume:11 Page:3080-3088
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Lin Jingchuan¹,Zhang Yu²^ORCID,Wang Jinxin³^ORCID,Han Xinyu³,Zhu Shenglan⁴,Li Tong³,Zhu Yanping⁵,Zhang Wei-Dong¹²³^ORCID

Affiliation:

1. School of Pharmacy, Dali University, Dali, 671003, China

2. Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, No. 1200, Cailun Road, Shanghai 201203, China

3. School of Pharmacy, Second Military Medical University, Shanghai 200433, China

4. Shanghai MicroPort Medical (Group) Co., Ltd, 1601 Zhangdong Road, ZJ Hi-Tech Park, Shanghai, 201203, China

5. School of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Shandong, Yantai 264005, China

Abstract

Herein, we describe a non-covalent complex-mediated epoxidation strategy that can yield highly selective central spiro-epoxides by irradiation with visible light without the need for catalyst addition.

Funder

Shanghai Education Development Foundation

Shanghai Municipal Education Commission

National Natural Science Foundation of China

National Basic Research Program of China

Science and Technology Commission of Shanghai Municipality

State Administration of Traditional Chinese Medicine of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00184B

Reference84 articles.

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