Recent advances in the synthesis of bridgehead (or ring-junction) nitrogen heterocycles via transition metal-catalyzed C–H bond activation and functionalization

Author:

Nie Biao12345,Wu Wanqing12345ORCID,Zhang Yingjun678910,Jiang Huanfeng12345ORCID,Zhang Ji678910

Affiliation:

1. Key Laboratory of Functional Molecular Engineering of Guangdong Province

2. School of Chemistry and Chemical Engineering

3. South China University of Technology

4. Guangzhou

5. China

6. State Key Laboratory of Anti-Infective Drug Development (NO. 2015DQ780357)

7. Sunshine Lake Pharma Co.

8. Ltd.

9. HEC R&D Center

10. Dongguan, 523871

Abstract

An update on recent advances in the synthesis of bridgehead nitrogen fused heterocycles via transition metal-catalyzed C–H activation and functionalization is reported.

Funder

National Major Science and Technology Projects of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference165 articles.

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2. Heterocyclic Chemistry , ed. J. A. Joule and K. Mills , Wiley , Chichester, WestSussex , 5th edn, 2010

3. Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products , ed. A. Padwa and W. H. Pearson , Wiley , New York, NY , 2002

4. Biosynthesis of Heterocycles, From Isolation to Gene Cluster , ed. P. Diana and G. Cirrincione , Wiley , Hoboken, NJ , 2015 , pp. 379–745

5. Contemporary Drug Synthesis , ed. J. J. Li , D. S. Johnson , D. R. Sliskovic and B. D. Roth , Wiley , Hoboken, NJ , 2004 , pp. 189–200

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