Discovery of new non-acidic lonazolac analogues with COX-2 selectivity as potent anti-inflammatory agents-Reference-Cited by-同舟云学术

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Discovery of new non-acidic lonazolac analogues with COX-2 selectivity as potent anti-inflammatory agents

Published:2019 Issue:10 Volume:10 Page:1775-1788
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Harras Marwa F.¹²³⁴⁵^ORCID,Sabour Rehab¹²³⁴⁵^ORCID,Alkamali Omkulthom Mohamed⁶⁷⁸⁹¹⁰

Affiliation:

1. Department of Pharmaceutical Chemistry

2. Faculty of Pharmacy (Girls)

3. Al-Azhar University

4. Cairo

5. Egypt

6. Department of Pharmaceutical Sciences

7. College of Pharmacy

8. Princess Nourah bint Abdulrahman University

9. Riyadh

10. Kingdom of Saudi Arabia

Abstract

Novel non-acidic lonazolac analogues with high COX-2 selectivity and good safety profile, having potential anti-inflammatory activity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00228F

Reference41 articles.

1. The Medicinal Timber Canarium patentinervium Miq. (Burseraceae Kunth.) Is an Anti-Inflammatory Bioresource of Dual Inhibitors of Cyclooxygenase (COX) and 5-Lipoxygenase (5-LOX)

2. Synthesis of novel celecoxib analogues by bioisosteric replacement of sulfonamide as potent anti-inflammatory agents and cyclooxygenase inhibitors

3. Cyclooxygenase inhibitors – current status and future prospects

4. Synthesis of 2,3-diaryl-1,3-thiazolidine-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors

5. Design and synthesis of 3-alkyl-2-aryl-1,3-thiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors

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