Cobalt carbonyl-catalyzed carbonylation of functionalized aziridines to versatile β-lactam building blocks

Author:

Piens Nicola12345ORCID,Van Hecke Kristof67845ORCID,Vogt Dieter910111213,D'hooghe Matthias12345ORCID

Affiliation:

1. SynBioC Research Group

2. Department of Sustainable Organic Chemistry and Technology

3. Faculty of Bioscience Engineering

4. Ghent University

5. B-9000 Ghent

6. XStruct

7. Department of Inorganic and Physical Chemistry

8. Faculty of Sciences

9. EaStCHEM

10. School of Chemistry

11. University of Edinburgh

12. Edinburgh EH9 3FJ

13. UK

Abstract

Aziridine to azetidin-2-one carbonylation as a convenient entry to pyrrolidines,C-fused bi- and tricyclic β-lactams and monocyclic carbapenem analogs.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference58 articles.

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2. Carbonylation of C (sp 3 ) X Bonds Utilizing CO;The Chemical Transformations of C1 Compounds;2022-01-21

3. Aziridines and 2H-Azirines: Monocyclic;Comprehensive Heterocyclic Chemistry IV;2022

4. Azetidines, Azetines and Azetes: Monocyclic;Comprehensive Heterocyclic Chemistry IV;2022

5. Other Fused Azetidines, Azetines and Azetes;Comprehensive Heterocyclic Chemistry IV;2022

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