ADMET-score – a comprehensive scoring function for evaluation of chemical drug-likeness-Reference-Cited by-同舟云学术

ADMET-score – a comprehensive scoring function for evaluation of chemical drug-likeness

Published:2019 Issue:1 Volume:10 Page:148-157
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Guan Longfei¹²³⁴⁵,Yang Hongbin¹²³⁴⁵^ORCID,Cai Yingchun¹²³⁴⁵,Sun Lixia¹²³⁴⁵,Di Peiwen¹²³⁴⁵,Li Weihua¹²³⁴⁵^ORCID,Liu Guixia¹²³⁴⁵^ORCID,Tang Yun¹²³⁴⁵^ORCID

Affiliation:

1. Shanghai Key Laboratory of New Drug Design

2. School of Pharmacy

3. East China University of Science and Technology

4. Shanghai 200237

5. China

Abstract

Chemical absorption, distribution, metabolism, excretion, and toxicity (ADMET), play key roles in drug discovery and development.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C8MD00472B

Reference49 articles.

1. Can the pharmaceutical industry reduce attrition rates?

2. 2017 FDA drug approvals

3. WITHDRAWN—a resource for withdrawn and discontinued drugs

4. A practical view of ‘druggability’

5. Understanding drug‐likeness

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