A mitochondria targeting artesunate prodrug-loaded nanoparticle exerting anticancer activity via iron-mediated generation of the reactive oxygen species-Reference-Cited by-同舟云学术

A mitochondria targeting artesunate prodrug-loaded nanoparticle exerting anticancer activity via iron-mediated generation of the reactive oxygen species

Published:2019 Issue:33 Volume:55 Page:4781-4784
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Chen Zhigang¹²³⁴⁵,Kang Xiaoxu⁶⁷⁸⁹¹⁰,Wu Yixin⁶⁷⁸⁹¹⁰,Xiao Haihua⁶⁷⁸⁹¹¹,Cai Xuzi¹²¹³¹⁴¹⁵⁹,Sheng Shihou¹⁶¹⁷⁹,Wang Xuefeng¹²¹³¹⁴¹⁵⁹,Chen Shiguo¹²³⁴⁵^ORCID

Affiliation:

1. Nanshan District Key Lab for Biopolymers and Safety Evaluation

2. Shenzhen Key Laboratory of Polymer Science and Technology

3. Guangdong Research Center for Interfacial Engineering of Functional Materials

4. College of Materials Science and Engineering

5. Shenzhen University

6. Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry

7. Chinese Academy of Sciences

8. Beijing 100190

9. P. R. China

10. College of Life Science and Technology

11. University of Chinese Academy of Sciences

12. Department of Obstetrics and Gynecology

13. Zhujiang Hospital

14. Southern Medical University

15. Guangzhou 510282

16. Department of Gastrointestinal Surgery China-Japan Union Hospital of Jilin University

17. Changchun 130033

Abstract

An artesunate anticancer prodrug with a long aliphatic chain N,N′-bis(dodecyl)-l-glutamic diamide was developed for nanoparticle via iron-mediated ROS generation.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC00531E

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