Use of an asparaginyl endopeptidase for chemo-enzymatic peptide and protein labeling-Reference-Cited by-同舟云学术

Use of an asparaginyl endopeptidase for chemo-enzymatic peptide and protein labeling

Published:2020 Issue:23 Volume:11 Page:5881-5888
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Tang T. M. Simon¹²³⁴^ORCID,Cardella Davide¹²³⁴^ORCID,Lander Alexander J.¹²³⁴^ORCID,Li Xuefei¹²³⁴,Escudero Jorge S.¹²³⁴,Tsai Yu-Hsuan¹²³⁴^ORCID,Luk Louis Y. P.¹²³⁴^ORCID

Affiliation:

1. School of Chemistry

2. Cardiff University

3. Cardiff

4. UK

Abstract

Asparaginyl endopeptidases (AEP) are ideal for peptide and protein labeling. Its pairing with a simple chemical reaction significantly lowers the amount of label needed for effective bioconjugation.

Funder

Biotechnology and Biological Sciences Research Council

Engineering and Physical Sciences Research Council

Royal Society of Chemistry

Wellcome Trust

Leverhulme Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC02023K