Facile fabrication of varisized calcium carbonate microspheres as vaccine adjuvants
Author:
Affiliation:
1. State Key Laboratory of Biochemical Engineering
2. PLA Key Laboratory of Biopharmaceutical Production & Formulation Engineering
3. Institute of Process Engineering
4. Chinese Academy of Sciences
5. Beijing
Abstract
HBsAg loaded CaCO3 microspheres with various diameters were fabricated via different mixing strategies and 1 μm particles has the strongest immune responses as vaccine adjuvant.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2017/TB/C6TB02845D
Reference60 articles.
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5. Mechanistic Insights into the Crystallization of Amorphous Calcium Carbonate (ACC)
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