Catalyst-free tandem Michael addition/decarboxylation of (thio)coumarin-3-carboxylic acids with indoles: facile synthesis of indole-3-substituted 3,4-dihydro(thio)coumarins
Author:
Affiliation:
1. College of Chemistry and Pharmaceutical Sciences
2. Qingdao Agricultural University
3. Qingdao, China
Abstract
The tandem Michael addition/decarboxylation of (thio)-coumarin-3-carboxylic acids with indoles gives biologically important indole-3-substituted dihydrocoumarins in good to excellent yields under catalyst-free conditions.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/OB/C3OB42582G
Reference41 articles.
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5. Simple indole alkaloids and those with a nonrearranged monoterpenoid unit
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