An intelligent T1–T2 switchable MRI contrast agent for the non-invasive identification of vulnerable atherosclerotic plaques-Reference-Cited by-同舟云学术

An intelligent T1–T2 switchable MRI contrast agent for the non-invasive identification of vulnerable atherosclerotic plaques

Published:2021 Issue:13 Volume:13 Page:6461-6474
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Pan Chunshu¹²³⁴⁵,Lin Junjie⁶⁷⁴⁵,Zheng Jianjun¹²³⁴⁵,Liu Chuang⁸⁹¹⁰¹¹¹²,Yuan Bo⁸⁹¹⁰¹¹¹²,Akakuru Ozioma Udochukwu⁸⁹¹⁰¹¹¹²^ORCID,Zubair Iqbal M.⁸⁹¹⁰¹¹¹²^ORCID,Fang Qianlan⁸⁹¹⁰¹¹¹²,Hu Jiapeng⁸⁹¹⁰¹¹¹²,Chen Jia⁸⁹¹⁰¹¹¹²,Lin Jie⁸⁹¹⁰¹¹¹²,Dai Qi¹²³⁴⁵,Guo Xiuyu¹²³⁴⁵,Li Zihou⁸⁹¹⁰¹¹¹²,Zhang Tao⁸⁹¹⁰¹¹¹²,Xu Chen¹²³⁴⁵,Ma Xuehua⁸⁹¹⁰¹¹¹²,Chen Tianxiang¹²³⁴⁵,Wu Aiguo⁸⁹¹⁰¹¹¹²^ORCID,Jin Yinhua¹²³⁴⁵^ORCID

Affiliation:

1. Department of Radiology

2. Hwa Mei Hospital

3. University of Chinese Academy of Sciences

4. Ningbo

5. China

6. Department of Anesthesiology

7. Ningbo Yinzhou No. 2 Hospital

8. Cixi Institute of Biomedical Engineering

9. International Cooperation Base of Biomedical Materials Technology and Application

10. Chinese Academy of Science (CAS) Key Laboratory of Magnetic Materials and Devices & Zhejiang Engineering Research Center for Biomedical Materials

11. Ningbo Institute of Materials Technology and Engineering

12. CAS

Abstract

A T₁–T₂ switchable MRI contrast agent, hyaluronic acid-modified iron oxide nanoparticle–polyacrylic acid, is used for the identification of vulnerable atherosclerotic plaques by macrophage phagocytosis. It could reveal promising enhancement in MRI.

Funder

National Natural Science Foundation of China

Zhejiang Province Public Welfare Technology Application Research Project

Natural Science Foundation of Zhejiang Province

Natural Science Foundation of Ningbo

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D0NR08039J

Reference53 articles.