A potent candidate against Zika virus infection: Synthesis, bioactivity, radiolabeling and biodistribution studies-Reference-Cited by-同舟云学术

A potent candidate against Zika virus infection: Synthesis, bioactivity, radiolabeling and biodistribution studies

Published:2022 Issue:39 Volume:46 Page:18764-18775
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Kumar Sumit¹,Sharma Neha²,Dantas Willyenne Marilia³⁴,do Nascimento Jessica Catarine Frutuoso³,Maus Hannah⁵^ORCID,de Oliveira Ronaldo Nascimento⁴,Pandit Unnat⁶,Singh Agam P.⁷^ORCID,Schirmeister Tanja⁵,Hazari Puja Panwar⁸,Pena Lindomar³,Poonam ¹⁹^ORCID,Rathi Brijesh²⁹^ORCID

Affiliation:

1. Department of Chemistry, Miranda House, University of Delhi, Delhi, 110007, India

2. Har Gobind Khorana Centre For Chemical Biology, Department of Chemistry, Hansraj College, University of Delhi, Delhi, 110007, India

3. Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz), Recife, 50670-420, Pernambuco, Brazil

4. Department of Chemistry, Federal Rural University of Pernambuco, Dois Irmãos, 52171-900, Recife, Brazil

5. Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, 55128, Mainz, Germany

6. Special Centre for Systems Medicine, Jawaharlal Nehru University, New Delhi, 110067, India

7. Infectious Diseases Laboratory, National Institute of Immunology, New Delhi, 110067, India

8. Division of Cyclotron and Radiopharmaceutical Sciences Institute of Nuclear Medicine and Allied Sciences, New Delhi, 110054, India

9. Delhi School of Public Health, Institution of Eminence, University of Delhi, Delhi, 110007, India

Abstract

Compound VI exhibits potent activity against Zika virus infection combined with favorable cellular uptake and biodistribution without apparent cytotoxicity in a mouse model.

Funder

Council of Scientific and Industrial Research, India

Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ02482A

Reference45 articles.

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3. Vector-borne transmission and evolution of Zika virus

4. The Unique Cofactor Region of Zika Virus NS2B–NS3 Protease Facilitates Cleavage of Key Host Proteins

5. Clinico-epidemiological and genomic profile of first Zika Virus outbreak in India at Jaipur city of Rajasthan state