A protein corona sensor array detects breast and prostate cancers

Author:

Digiacomo Luca1234,Jafari-Khouzani Kourosh567,Palchetti Sara1234,Pozzi Daniela1234ORCID,Capriotti Anna Laura8294,Laganà Aldo8294,Zenezini Chiozzi Riccardo1011121314,Caputo Damiano1516174,Cascone Chiara1516174,Coppola Roberto1516174ORCID,Flammia Gerardo1819174,Altomare Vittorio2019174,Grasso Antonella2019174,Mahmoudi Morteza21227ORCID,Caracciolo Giulio1234ORCID

Affiliation:

1. Department of Molecular Medicine

2. “Sapienza” University of Rome

3. 00161 Rome

4. Italy

5. IBM Watson Health

6. Cambridge

7. USA

8. Department of Chemistry

9. 00185 Rome

10. Biomolecular Mass Spectrometry and Proteomics

11. Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences

12. Utrecht University

13. Utrecht

14. the Netherlands

15. Department of General Surgery

16. University Campus-Biomedico di Roma

17. 00128 Rome

18. Department of Urology

19. University Campus Bio-Medico di Roma

20. Breast Unit

21. Precision Health Medicine

22. Department of Radiology Michigan State University

Abstract

Following exposure to human plasma nanoparticles are coated with a “disease-specific” protein corona.

Funder

Associazione Italiana per la Ricerca sul Cancro

Fondazione Italiana per la Ricerca sul Cancro

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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