Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential

Author:

Sun Cheng-Peng12345ORCID,Oppong Mahmood Brobbey1234,Zhao Feng678910,Chen Li-Xia51112813,Qiu Feng12345ORCID

Affiliation:

1. Tianjin State Key Laboratory of Modern Chinese Medicine and School of Chinese Materia Medica

2. Tianjin University of Traditional Chinese Medicine

3. Tianjin 300193

4. China

5. Department of Natural Products Chemistry

6. School of Pharmacy

7. Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)

8. Ministry of Education

9. Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong

10. Yantai University

11. School of Traditional Chinese Materia Medica

12. Key Laboratory of Structure-Based Drug Design & Discovery

13. Shenyang Pharmaceutical University

Abstract

Aromaphysalin B (2), as a first 11,15-cyclo-9(10),14(17),22(26)-triseco physalin with an unprecedented aromatic ring, was isolated from Physalis angulata.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference35 articles.

1. Natural withanolides: an overview

2. Antileishmanial Physalins fromPhysalis minima

3. A. S. Veleiro , J. C.Oberti and G.Burton, Studies in natural products chemistry, bioactive natural products, 2005, vol. 32, pp. 1019–1052

4. A. S. R. Anjaneyulu , D. S.Rao and P. W.Lequesne, Studies in natural products chemistry, bioactive natural products, 1998, vol. 20, pp. 135–261

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