Quantitative proteomic analysis of HeLa cells in response to biocompatible Fe2C@C nanoparticles: 16O/18O-labelling & HPLC-ESI-orbit-trap profiling approach

Author:

Hasan Murtaza12345,Mustafa Ghazala6783,Iqbal Javed9101112,Ashfaq Muhammad123,Mahmood Nasir1314151617ORCID

Affiliation:

1. Department of Biochemistry and Biotechnology

2. The Islamia University of Bahawalpur

3. Pakistan

4. Department of Materials Science and Engineering

5. College of Engineering

6. Department of Plant Sciences

7. Quaid-i-Azam University

8. Islamabad 45320

9. College of Life Sciences

10. Shenzhen University

11. Shenzhen 10590

12. China

13. School of Engineering

14. RMIT University

15. 3001 Melbourne

16. Australia

17. Center of Micro-Nano Functional Materials and Devices

Abstract

Here, we have investigated the comparative quantitative proteomics analysis of the molecular response of HeLa cells to biocompatible Fe2C@C nanoparticles (NPs) using 16O/18O isotopic labelling of the cell culture.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

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