Miniaturised broth microdilution for simplified antibiotic susceptibility testing of Gram negative clinical isolates using microcapillary devices

Author:

Needs Sarah H.1ORCID,Saiprom Natnaree2,Rafaque Zara3,Imtiaz Wajiha4,Chantratita Narisara2,Runcharoen Chakkaphan2,Thammachote Jeeranan5,Anun Suthatip5,Peacock Sharon J.6,Ray Partha78,Andrews Simon4ORCID,Edwards Alexander D.19ORCID

Affiliation:

1. School of Pharmacy, University of Reading, RG6 6DX, UK

2. Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Thailand

3. Department of Microbiology, Faculty of Health Sciences, Hazara University, Mansehra, Pakistan

4. School of Biological Sciences, University of Reading, RG6 6DX, UK

5. Division of Clinical Microbiology, Medical Technology Department, Bhuddhasothon Hospital, Chachoengsao, Thailand

6. Department of Medicine, University of Cambridge, UK

7. The Nature Conservancy, Virginia, USA

8. School of Agriculture Policy and Development, University of Reading, UK

9. CFT Ltd, Daux Road, Billingshurst, RH14 9SJ, UK

Abstract

Miniaturised antibiotic susceptibility testing: 100 times smaller microcapillary broth microdilution gives equivalent result to standard microplate broth microdilution.

Funder

Engineering and Physical Sciences Research Council

Commonwealth Scholarship Commission

Higher Education Commission, Pakistan

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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