The EcCLC antiporter embedded in lipidic liquid crystalline films – molecular dynamics simulations and electrochemical methods

Author:

Miszta Przemysław12,Nazaruk Ewa2ORCID,Nieciecka Dorota2,Możajew Mariusz123ORCID,Krysiński Paweł2ORCID,Bilewicz Renata12ORCID,Filipek Sławomir12ORCID

Affiliation:

1. Biological and Chemical Research Centre, University of Warsaw, Zwirki i Wigury 101, 02-089 Warsaw, Poland

2. Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland

3. Nencki Institute of Experimental Biology, Polish Academy of Sciences, Pasteura 3, 02-093 Warsaw, Poland

Abstract

Lipidic-liquid crystalline nanostructures (lipidic cubic phases), which are biomimetic and stable in an excess of water, were used as a convenient environment to investigate the transport properties of the membrane antiporter E. coli CLC-1 (EcCLC).

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

European Social Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

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