Substrate specificity of FUT8 and chemoenzymatic synthesis of core-fucosylated asymmetric N-glycans
Author:
Affiliation:
1. Department of Chemistry and Center for Diagnostics & Therapeutics
2. Georgia State University
3. Atlanta
4. USA
5. Chemily LLC
6. Department of Chemistry
7. University of California
8. Davis
Abstract
Based on substrate specificity of human FUT8, an efficient strategy was developed for the synthesis of core-fucosylated asymmetric N-glycans.
Funder
National Cancer Institute
National Institute of General Medical Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB00586A
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