Stiffness can mediate balance between hydrodynamic forces and avidity to impact the targeting of flexible polymeric nanoparticles in flow

Author:

Farokhirad Samaneh1234ORCID,Ranganathan Abhay1534,Myerson Jacob16734,Muzykantov Vladimir R.16734,Ayyaswamy Portonovo S.1234,Eckmann David M.15341,Radhakrishnan Ravi18341ORCID

Affiliation:

1. University of Pennsylvania

2. Department of Mechanical Engineering and Applied Mechanics

3. Philadelphia

4. USA

5. Department of Anesthesiology and Critical Care

6. Center for Targeted Therapeutics and Translational Nanomedicine

7. Institute for Translational Medicine & Therapeutics and Department of Pharmacology

8. Department of Bioengineering

Abstract

Computational investigations of deformable polymeric nanoparticles under flow and adhesive environment.

Funder

National Institute of Biomedical Imaging and Bioengineering

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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