Hexaphenyl-1,3-butadiene derivative: a novel “turn-on” rapid fluorescent probe for intraoperative pathological diagnosis of hepatocellular carcinoma

Author:

Chen Didi1234,Mao Huiling56784,Hong Yuning910111213ORCID,Tang Yong141516173,Zhang Yong141516173,Li Min141516173ORCID,Dong Yuping56784ORCID

Affiliation:

1. Hubei Key Laboratory of Purification and Application of Plant Anti-cancer Active Ingredients

2. Hubei University of Education

3. Wuhan

4. China

5. Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications

6. School of Materials Science and Engineering

7. Beijing Institute of Technology

8. Beijing

9. Department of Chemistry and Physics

10. La Trobe Institute for Molecular Science

11. La Trobe University

12. Melbourne

13. Australia

14. Department of Hepatobiliary Surgery

15. Union Hospital

16. Tongji Medical College

17. Huazhong University of Science and Technology

Abstract

The staining method based on AIE-active ZZ-HPB-NC can simple distinguish the hepatocellular carcinoma from liver noncancerous tissue, which overcomes the drawbacks of the poor anti-interference ability of the authoritative clinical H&E technique.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Materials Science

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