Co-delivery of proapoptotic peptide and p53 DNA by reduction-sensitive polypeptides for cancer therapy-Reference-Cited by-同舟云学术

Co-delivery of proapoptotic peptide and p53 DNA by reduction-sensitive polypeptides for cancer therapy

Published:2015 Issue:5 Volume:3 Page:753-763
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Chen Si¹²³⁴,Rong Lei¹²³⁴,Jia Hui-Zhen¹²³⁴,Qin Si-Yong¹²³⁴,Zeng Xuan¹²³⁴,Zhuo Ren-Xi¹²³⁴,Zhang Xian-Zheng¹²³⁴

Affiliation:

1. Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry

2. Wuhan University

3. Wuhan 430072

4. PR China

Abstract

The xPolyR₈–KLA(TPP)/p53 complex releases the p53 gene and C-KLA(TPP) in the cytoplasm, and initiates a more efficient cell apoptosis due to the regulation of both apoptotic pathways through p53 and C-KLA(TPP).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2015/BM/C5BM00046G

Reference43 articles.

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3. Forcing Cancer Cells to Commit Suicide

4. Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR8Peptide/p53 DNA for Cocktail Therapy

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