Design, synthesis, pharmacological evaluation, and <i>in silico</i> studies of the activity of novel spiro pyrrolo[3,4-<i>d</i>]pyrimidine derivatives-Reference-Cited by-同舟云学术

Design, synthesis, pharmacological evaluation, and in silico studies of the activity of novel spiro pyrrolo[3,4-d]pyrimidine derivatives

Published:2024 Issue:2 Volume:14 Page:995-1008
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Alzahrani Abdullah Y. A.¹,Shehab Wesam S.²^ORCID,Amer Asmaa H.²,Assy Mohamed G.²,Mouneir Samar M.³^ORCID,Aziz Maged A.²,Abdel Hamid Atef M.²

Affiliation:

1. Department of Chemistry, Faculty of Science and Arts, King Khalid University, Mohail Assir, Saudi Arabia

2. Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt

3. Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Cairo, 12211, Egypt

Abstract

In the present study, spiro compounds are shown to have distinctive characteristics because of their interesting conformations and their structural impacts on biological systems.

Funder

King Khalid University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA07078F

Reference76 articles.

1. Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review

2. Design, synthesis and evaluations of spiro‐fused benzoxaborin derivatives as novel boron‐containing compounds

3. MgO‐Nanoparticle‐Catalyzed Synthesis and Evaluation of Antimicrobial and Antioxidant Activity of New Multi‐Ring Compounds Containing Spiro[indoline‐3,4′‐[1,3]dithiine]

4. Recent advances in chemistry and pharmacological aspects of 2-pyridone scaffolds

5. Synthesis and study of antibacterial and antifungal activities of novel 8-methyl-7,9-diaryl-1,2,4,8-tetraazaspiro[4.5]decan-3-thiones