CuS@PDA–FA nanocomposites: a dual stimuli-responsive DOX delivery vehicle with ultrahigh loading level for synergistic photothermal–chemotherapies on breast cancer

Author:

Zhang Shang-Qing12345,Liu Xun12345,Sun Qi-Xuan12345,Johnson Omar6789,Yang Ting12345ORCID,Chen Ming-Li12345ORCID,Wang Jian-Hua12345ORCID,Chen Wei6789ORCID

Affiliation:

1. Research Center for Analytical Sciences

2. Department of Chemistry

3. College of Sciences

4. Northeastern University

5. Shenyang 110819

6. Department of Physics

7. The University of Texas at Arlington

8. Arlington

9. USA

Abstract

CuS@PDA nanoparticles were synthesized and used to create a novel tumor-targeting nanocomposite platform composed of copper sulfide@polydopamine–folic acid/doxorubicin for performing both photothermal and chemotherapeutic cancer treatment.

Funder

National Natural Science Foundation of China

National Institutes of Health

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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