Advances in research on 3C-like protease (3CL<sup>pro</sup>) inhibitors against SARS-CoV-2 since 2020-Reference-Cited by-同舟云学术

Advances in research on 3C-like protease (3CL^pro) inhibitors against SARS-CoV-2 since 2020

Published:2023 Issue:1 Volume:14 Page:9-21
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Chen Roufen¹,Gao Yali²,Liu Han¹,Li He¹,Chen Wenfa²,Ma Junjie¹^ORCID

Affiliation:

1. School of Medicine, Huaqiao University, Quanzhou, 362000, China

2. Pharmacy Department, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, China

Abstract

The representative SARS-CoV-2 3CLpro inhibitors reported since 2020 and their biological activities and binding models are reviewed, providing new insights into the design and development of more effective 3CLpro inhibitors against SARS-CoV-2.

Funder

Fujian Provincial Health Technology Project

Fujian Medical University

Natural Science Foundation of Fujian Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D2MD00344A

Reference77 articles.

1. WHO COVID-19 Explorer , World Health Organization , Geneva , https://worldhealthorg.shinyapps.io/covid/ , (accessed August 2020 )

2. Recent Smell Loss Is the Best Predictor of COVID-19 Among Individuals With Recent Respiratory Symptoms

3. Self-reported Olfactory and Taste Disorders in Patients With Severe Acute Respiratory Coronavirus 2 Infection: A Cross-sectional Study

4. The impact of the coronavirus (COVID-19) pandemic on individuals with gastrointestinal disorders: A protocol of an international collaborative study

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